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Sildenafil inhibits the work of an enzyme called phosphodiesterase type 5 and enhances the action of nitric oxide. This helps to:
The active ingredient of COBRA 120mg is 120 mg of sildenafil citrate. It belongs to the class of medicines known kakım PDE-5 inhibitors. Sildenafil increases blood flow to the penis following sexual stimulation and does this by blocking the enzyme responsible for cGMP breakdown.
Nitric oxide then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood .
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Patients may benefit from therapy when the causes of the disorder are either understood or derece known.
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The safety and efficacy of sildenafil for the treatment of PAH in children below 1 year of age özgü not been established as no veri is available .
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This website is using a security service to burayı kontrol et protect itself from online attacks. The action you just performed triggered the security solution. There are several actions that could trigger this block including submitting a certain word or phrase, a SQL command or Burada malformed veri.
Keep in mind that the original Cobra 120 does not produce an erection by itself. You need sexual stimulation for the pills to work and the penis to fill with blood.
Moreover, apart from the Burada presence of PDE5 in the corpus cavernosum of the penis, PDE5 is also present in the pulmonary İnternet sitesi vasculature . Cobra, therefore, increases cGMP within pulmonary vascular smooth muscle cells resulting in relaxation .
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